Abstracts

CALL FOR ABSTRACTS

Fifth Annual RECOMB Satellite meeting on DNA Sequencing Technologies and Computation

May 21-22, James H Clark Center, Stanford University, Stanford, CA

Genome sequencing has been truly flourishing the past several years. The completion of the human genome in April 2003 marked the beginning of a new era in genetics. Together with the mouse, rat, dog, chimpanzee, chicken, and hundreds of other genomes, scientists are obtaining the basis for studying biology at the nucleotide level. The recent achievements have been possible because of advances in both sequencing technology and computational methods for genomic assembly.

Demand for sequencing is not decreasing, however, but rather increasing. On the one hand, cross-species comparison is the most fruitful way to computationally analyze sequences and find regions of evolutionary
constraint. For that reason, it is desirable to sequence as many species as possible: several yeast or Drosophila strains are being analyzed by cross-species comparisons, and there are plans for large-scale mammalian
sequencing. On the other hand, the ultimate goal is medicine, where inexpensive resequencing of a full human genome would have vast implications. The immediate future of sequencing promises to be very exciting, on the one hand with large ongoing sequencing projects, and on the other hand with development of many novel sequencing technologies that promise to enable sequencing of a large genome for as little as $1000.

The goal of this meeting is to bring together people from different disciplines of genome sequencing. We will cover exciting ongoing projects such as sequencing of environmental samples; on the technology front we will cover new technologies having potential of reducing the cost of genome sequencing to a few 1000 dollars, including, miniaturized sequencing-by-synthesis, sequencing-by-hybridization, single-molecule techniques, and fragmentation-based techniques. On the computation side, we will examine new algorithmic problems that arise by such technologies, as well as application and continuing development of current assembly systems., and applications of genome data to systems biology.

Topics include, but are not limited to:

Successful submissions will be invited for a 15-minute presentation, and a 1-2 page abstract will be printed on the conference proceedings, to be distributed to the meeting attendees.

Abstracts should be 1 to 2 pages, and submitted in plain text or PDF format.